ELK Biotechnology RO52 rabbit pAb
RO52 단백질을 인식하는 토끼 폴리클로날 항체로 WB 및 ELISA에 적합합니다. 인간, 랫, 마우스 시료에 반응하며, 높은 특이성과 안정성을 제공합니다. -20°C에서 1년간 보관 가능하며 농도는 1 mg/ml입니다.
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제품명
RO52 rabbit pAb
공급업체
ELK Biotechnology
제품 설명
RO52 단백질을 인식하는 토끼 폴리클로날 항체입니다. 인간, 랫, 마우스 시료에 반응하며, Western Blot(WB) 및 ELISA 분석에 적합합니다.
제품 스펙
| 항목 | 내용 |
|---|---|
| Applications | WB; ELISA |
| Recommended Dilutions | WB 1:500–2000, ELISA 1:5000–20000 |
| Immunogen | Synthesized peptide derived from human protein (AA range: 140–220) |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 52 kD |
| GeneID (Human) | 6737 |
| Human Swiss-Prot No | P19474 |
| Species Reactivity | Human; Rat; Mouse |
| Cellular Localization | Cytoplasm, cytoplasmic vesicle, autophagosome, nucleus, P-body. Enters the nucleus upon exposure to nitric oxide. Localizes to small dot- or rod-like structures (P-bodies) near the plasma membrane and diffusely in the cytoplasm. Colocalizes with DCP2 in P-bodies. |
Background
This gene encodes a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains (RING, B-box type 1, B-box type 2) and a coiled-coil region. The encoded protein is part of the RoSSA ribonucleoprotein, which includes a single polypeptide and one of four small RNA molecules. The RoSSA particle localizes to both cytoplasm and nucleus and interacts with autoantigens in patients with Sjogren syndrome and systemic lupus erythematosus. Alternatively spliced transcript variants have been described, but the full-length nature of only one has been determined. [RefSeq, Jul 2008]
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