ELK Biotechnology ABCCB rabbit pAb
ABCCB 단백질을 인식하는 토끼 폴리클로날 항체로 WB 및 ELISA에 사용 가능. 인간, 랫, 마우스 시료에 반응. 고순도 IgG, 1 mg/ml 농도. 세포막 및 소포막 단백질 검출에 적합.
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제품명
ABCCB rabbit pAb
제품 개요
ELK Biotechnology에서 제공하는 ABCCB 단백질에 대한 토끼 폴리클로날 항체입니다. ATP-binding cassette(ABC) 수송체 슈퍼패밀리 단백질 검출에 사용되며, 다중 약물 저항성 관련 연구에 적합합니다.
제품 정보
| 항목 | 내용 |
|---|---|
| Applications | WB; ELISA |
| Recommended Dilutions | WB: 1:500–2000, ELISA: 1:5000–20000 |
| Immunogen | Synthesized peptide derived from human protein (AA range: 50–130) |
| Species Reactivity | Human; Rat; Mouse |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 152 kD |
| Gene ID (Human) | 85320 |
| Human Swiss-Prot No | Q96J66 |
| Cellular Localization | Cell membrane; Multi-pass membrane protein; Vacuole membrane; Cytoplasmic vesicle membrane; Apical cell membrane |
| Storage | -20°C / 1 year |
| Host | Rabbit |
Background
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White).
This ABC full transporter belongs to the MRP subfamily involved in multi-drug resistance. It participates in physiological processes involving bile acids, conjugated steroids, and cyclic nucleotides.
A SNP in this gene determines human earwax type. This gene and its family member ABCC12 are derived by duplication and both localized to chromosome 16q12.1. Multiple alternatively spliced transcript variants have been described for this gene.
[provided by RefSeq, Jul 2008]
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