ELK Biotechnology PSD13 rabbit pAb
PSD13 단백질을 인식하는 토끼 폴리클로날 항체로, WB와 ELISA에 사용 가능. 인간, 생쥐, 랫트 반응성. 고순도 IgG, 1 mg/ml 농도. -20°C에서 1년 보관 가능. 프로테아좀 복합체 연구에 적합.
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PSD13 rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Applications | WB; ELISA |
| Recommended Dilutions | WB 1:500–2000, ELISA 1:5000–20000 |
| Immunogen | Synthesized peptide derived from human protein (AA range: 260–340) |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 41 kD |
| Gene ID (Human) | 5719 |
| Human Swiss-Prot No | Q9UNM6 |
| Cellular Localization | Proteasome complex, nucleus, nucleoplasm, cytosol, proteasome regulatory particle, lid subcomplex, membrane, proteasome accessory complex, extracellular exosome |
| Species Reactivity | Human; Mouse; Rat |
| Storage | -20°C, 1 year |
Background
The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of two complexes: a 20S core and a 19S regulator.
The 20S core consists of four rings of 28 non-identical subunits (two rings of seven alpha subunits and two rings of seven beta subunits).
The 19S regulator includes a base (6 ATPase subunits and 2 non-ATPase subunits) and a lid (up to 10 non-ATPase subunits).
Proteasomes are widely distributed in eukaryotic cells and cleave peptides in an ATP/ubiquitin-dependent, non-lysosomal pathway.
A modified proteasome, the immunoproteasome, is essential for processing class I MHC peptides.
This gene encodes a non-ATPase subunit of the 19S regulator. Two transcripts encoding different isoforms have been described.
[provided by RefSeq, Jul 2008]
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