Thermo Fisher Scientific Caspase 6 Monoclonal Antibody (MCH2 14 1-190)
Caspase-6 단백질을 표적으로 하는 Mouse monoclonal antibody로 Western blot에 적합. 인간 시료에 반응하며 1 mg/mL 농도의 액상 형태. MCF-7 cell lysate를 양성 대조로 권장. 연구용으로만 사용 가능.
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Thermo Fisher Scientific Caspase 6 Monoclonal Antibody (MCH2 14 1-190)
Applications
- Western Blot (WB)
Tested Dilution: 1:500
Publications: -
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG |
| Class | Monoclonal |
| Type | Antibody |
| Clone | MCH2 14 1-190 |
| Immunogen | Recombinant human caspase-6 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS |
| Contains | 0.08% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_1071008 |
Product Specific Information
A suggested positive control for this product is MCF-7 cell lysate.
Target Information
Caspases are cysteine proteases expressed as inactive precursors that mediate apoptosis by proteolysis of specific substrates.
They cleave after aspartic acid residues and are divided into two classes involved in apoptosis:
- Initiator caspases (activated by receptor clustering)
- Effector caspases (activated by mitochondrial permeability transition)
Proapoptotic signals autocatalytically activate initiator caspases such as Caspase-8 and Caspase-9.
Activated initiator caspases then process effector caspases such as Caspase-3 and Caspase-7, which lead to cell collapse.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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