
Thermo Fisher Scientific LRRK2 Polyclonal Antibody
LRRK2 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, WB, IHC, ICC/IF 등 다양한 응용 가능. 인간, 마우스, 랫트 등 반응. 항원 친화 크로마토그래피로 정제되었으며, 4°C에서 보관.
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Thermo Fisher Scientific LRRK2 Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-Dependent |
| Immunohistochemistry (Frozen) (IHC (F)) | Assay-Dependent |
| Immunocytochemistry (ICC/IF) | 1:500–1:1,000 |
| Flow Cytometry (Flow) | Assay-Dependent |
| Immunoprecipitation (IP) | 1:10–1:500 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Non-human primate, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to C-terminal region (residues 2500–2527) of human LRRK2 protein, conjugated to KLH |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7–8 |
| Contains | 0.02% sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Wet ice |
| RRID | AB_2137906 |
Product Specific Information
Suggested positive control:
- Human lymphoblasts for IHC
- Human and mouse brain for Western blot
Target Information
LRRK2 (Leucine-rich repeat kinase 2) is a multidomain protein containing kinase, GTPase, and leucine-rich repeat domains. Mutations in LRRK2 are linked to Parkinson’s disease. The protein includes ankyrin repeat, LRR, kinase, DFG-like, RAS, GTPase, MLK-like, and WD40 domains. It is primarily cytoplasmic but also associates with the mitochondrial outer membrane.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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