Thermo Fisher Scientific Growth Hormone (Pituitary Marker) Monoclonal Antibody (GH/1450)
인체 성장호르몬(GH)을 표적으로 하는 마우스 단클론 항체로, 뇌하수체 마커 연구에 적합합니다. 파라핀 및 PFA 고정 조직의 IHC에 사용 가능하며, 고순도 Protein A/G 정제 및 안정적 PBS 버퍼 제공. 연구용으로만 사용됩니다.
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Thermo Fisher Scientific Growth Hormone (Pituitary Marker) Monoclonal Antibody (GH/1450)
Applications
Immunohistochemistry (Paraffin) (IHC (P))
Assay-dependentImmunohistochemistry (PFA fixed) (IHC (PFA))
0.1–0.2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | GH/1450 |
| Immunogen | Recombinant fragment (around aa58–187) of human Growth Hormone (GH) protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Human growth hormone (hGH) is a member of the somatotropin/prolactin family of hormones that play an important role in growth control.
The GH1 gene, along with four related genes, is located at the growth hormone locus on chromosome 17, sharing a high degree of sequence identity.
Alternative splicing results in five isoforms ranging from approximately 19 kDa to 24 kDa.
hGH is produced by somatotroph cells in the pituitary and acts via cytokine receptor subfamily membrane receptors.
Its major role is to stimulate body growth by inducing the liver and other tissues to secrete IGF-1.
It promotes differentiation and proliferation of myoblasts, amino acid uptake, and protein synthesis in muscle and other tissues.
Mutations or deletions in the gene lead to growth hormone deficiency and short stature.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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