Thermo Fisher Scientific MC1 Receptor Polyclonal Antibody
MC1 수용체에 특이적인 Rabbit Polyclonal Antibody로 사람 및 랫트 반응성. Western blot, IHC, ICC/IF에 사용 가능. 항원 친화 크로마토그래피로 정제된 동결건조 형태. 멜라닌 생성 조절 연구에 적합.
- 카탈로그번호
- AMR-020-xxxxx (3개 옵션)
- 판매단위
- pk
카탈로그
3개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific MC1 Receptor Polyclonal Antibody
Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:400 | - |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100 | - |
| Immunocytochemistry (ICC/IF) | 1:200 | - |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Rat |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | (C)HAQGIARLHKRQRPVH, corresponding to amino acid residues 217–232 of human MC1R, 3rd intracellular loop |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.6 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 1% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Reconstitution: Add 25 µL, 50 µL, or 0.2 mL of double distilled water (DDW), depending on sample size.
The antibody ships as a lyophilized powder at room temperature. Upon arrival, store at -20°C.
Reconstituted solution can be stored at 4°C for up to 1 week. For longer storage, aliquot and keep at -20°C.
Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10,000 × g, 5 min).
Target Information
MC1R (Melanocortin Receptor 1) mediates the effects of melanocyte-stimulating hormone (MSH) and adrenocorticotropic hormone (ACTH).
MSH and MC1R regulate melanogenesis, controlling the balance between red pheomelanin and black eumelanin in the skin.
Non-functional receptors lead to lighter pigmentation, while constitutively active receptors result in darker color.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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