Thermo Fisher Scientific ARIP4 Polyclonal Antibody
Thermo Fisher Scientific의 ARIP4 Polyclonal Antibody는 인간 RAD54L2(ARIP4)를 인식하는 토끼 유래 IgG 항체로, WB, IHC, IP 등 다양한 응용에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, 4°C에서 보관합니다. 연구용 전용 제품입니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000–1:10,000 |
| Immunohistochemistry (IHC) | 1:100–1:500 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:500 |
| Immunoprecipitation (IP) | 2–5 µg/mg lysate |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 75 and 125 of human androgen receptor-interacting protein 4 (RAD54-like 2) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.20 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | TBS, pH 7.0–8.0, with 0.1% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- For IHC, epitope retrieval with citrate buffer (pH 6.0) is recommended for FFPE tissue sections
- Based on 100% sequence identity, this antibody is predicted to react with Mouse
Target Information
Adrenergic receptors (ARs) include four general types (α1, α2, β1, and β2), found in different tissues and differing in affinities and responses to various agonists and antagonists. The coupling of ARs to intracellular effectors is mediated by heterotrimeric G proteins. ARs play a critical role in prostate cancer development, and AR transcriptional activity is regulated by coregulatory proteins.
RAD54L2 (RAD54-like 2), also known as ARIP4 (androgen receptor-interacting protein 4), HSPC325, or SRISNF2L, is a 1,467 amino acid nuclear protein of the SNF2/RAD54 helicase family. It contains a helicase ATP-binding domain and a helicase C-terminal domain. RAD54L2 functions as a DNA helicase that regulates androgen receptor-dependent transactivation in a promoter-dependent manner and is post-translationally modified (sumoylated or phosphorylated) upon DNA damage.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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