Thermo Fisher Scientific ARIP4 Polyclonal Antibody
Rabbit polyclonal antibody against ARIP4 (RAD54L2) for WB, IHC, IHC-P, and IP applications. Recognizes human ARIP4 region 75–125. Unconjugated, liquid form, 0.2 mg/mL concentration. Recommended storage at 4°C, shelf life 1 year. For research use only.
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Thermo Fisher Scientific ARIP4 Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000–1:10,000 |
| Immunohistochemistry (IHC) | 1:100–1:500 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:100–1:500 |
| Immunoprecipitation (IP) | 2–5 µg/mg lysate |
Product Specifications
| Property | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 75 and 125 of human androgen receptor-interacting protein 4 (RAD54-like 2) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.20 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- For IHC, epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections
- Based on 100% sequence identity, this antibody is predicted to react with Mouse
Target Information
Adrenergic receptors (ARs) include four general types (α1, α2, β1, and β2) that differ in tissue distribution and responses to agonists and antagonists. These receptors couple to intracellular effectors via heterotrimeric G proteins and play critical roles in prostate cancer development.
RAD54L2 (RAD54-like 2), also known as ARIP4 (androgen receptor-interacting protein 4), HSPC325, or SRISNF2L, is a 1,467 amino acid nuclear protein of the SNF2/RAD54 helicase family. It contains helicase ATP-binding and C-terminal domains. RAD54L2 acts as a DNA helicase regulating AR-dependent transcription in a promoter-dependent manner and undergoes post-translational modifications such as sumoylation or phosphorylation upon DNA damage.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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