Thermo Fisher Scientific NHERF1 Polyclonal Antibody
Thermo Fisher Scientific의 NHERF1 Polyclonal Antibody는 Rabbit IgG 기반의 비결합 액상 항체로, Western Blot에 최적화되어 있습니다. NHERF1/EBP50 단백질 연구에 적합하며, 세포 접합부 및 단백질 상호작용 연구에 활용됩니다. 연구용으로만 사용 가능합니다.
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Applications
- Western Blot (WB)
Tested Dilution: 1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Between 225 and 275 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Target Information
NHERF1 (Na+/H+ exchanger regulatory factor 1), also known as EBP50 (ezrin, radixin, moesin-binding phosphoprotein 50), is an adaptor protein that associates with beta-catenin and is required for its localization at cell-cell junctions.
It interacts with various G protein-coupled receptors and regulates their trafficking, as well as sodium-hydrogen exchange and sodium-dependent phosphate transport.
NHERF1/EBP50 inhibits cell motility and is required to suppress anchorage-independent growth. It contains a C-terminal ERM (ezrin, radixin, moesin)-binding region and two N-terminal PDZ (postsynaptic-density-95/disc-large/ZO1 homology) domains, enabling head-to-tail intramolecular conformation to regulate its interactions.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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