
Thermo Fisher Scientific Plasminogen Polyclonal Antibody
인간 Plasminogen을 인식하는 양 폴리클로날 항체로 Western blot 및 ELISA에 적합합니다. 고농도(15.9 mg/mL) 액상 형태이며 SDS-PAGE로 정제되었습니다. -20°C에서 보관하며 연구용으로 사용됩니다.
- 카탈로그번호
- PA143053
- 판매단위
- pk
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Thermo Fisher Scientific Plasminogen Polyclonal Antibody
Applications and Tested Dilution
- Western Blot (WB): 25 µg/mL
- ELISA: 5–10 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Sheep / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Human Plasminogen |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 15.9 mg/mL |
| Purification | SDS-PAGE |
| Storage Buffer | 50% water with 50% glycerol |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_1086709 |
Product Specific Information
PA1-43053 detects Plasminogen in human samples.
It has been successfully used in Western blot and ELISA applications.
PA1-43053 was derived from human plasminogen.
Target Information
Plasminogen is a plasma protein synthesized mostly in the liver. It consists of a single polypeptide chain with a molecular weight of approximately 88.5 kDa. The plasma concentration typically ranges from 70 to 200 mg/L.
Activation of plasminogen by tissue-plasminogen activator, urokinase, or streptokinase produces plasmin through cleavage and release of the preactivation peptide.
Plasmin consists of a heavy (A-) chain containing five kringles and a light (B-) chain harboring the active site. It is a trypsin-like protease that acts on fibrin, with kringle domains mediating fibrin binding.
Plasmin plays a crucial role in fibrinolysis, and congenital defects in plasmin can lead to recurrent thrombosis, thrombophlebitis, and pulmonary embolism.
Usage Note
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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