Thermo Fisher Scientific PYY Polyclonal Antibody, MaxPab
Rabbit polyclonal antibody against human PYY protein. Validated for Western blot applications. Affinity purified and supplied in PBS buffer without preservatives. Suitable for research use in studies of appetite regulation and gut hormone signaling.
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- pk
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Applications
- Western Blot (WB): 1–5 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Full-length human PYY protein (AAH41057.1, amino acids 1–97) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, avoid freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
MVFVRRPWPA LTTVLLALLV CLGALVDAYP IKPEAPGEDA SPEELNRYYA SLRHYLNLVT RQRYGKRDGP DRLLSKTFFP DGEDRPVRSR SEGPDLW
Target Information
Peptide YY (PYY), also known as peptide tyrosine-tyrosine amide (3-36), is a gut hormone metabolite produced by dipeptidyl peptidase IV activity on PYY in the intestinal brush border and circulation. PYY (3-36) acts as a potent inhibitor of food intake in rats and humans by selectively binding to the Y2 receptor, inhibiting orexigenic NPY neurons in the arcuate nucleus, and disinhibiting anorexigenic POMC neurons. Its anorexigenic effects are additive with those of the co-secreted hormone GLP-1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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