Thermo Fisher Scientific Galectin-3 (LGALS3) (Thyroid Cell Marker) Monoclonal Antibody (LGALS3/4792)
인간 Galectin-3(LGALS3)을 표적하는 단클론 항체로 갑상선 세포 마커로 사용 가능. IHC 및 Peptide Array에 적용 가능. 고순도 Protein A/G 정제, 무보존액 PBS 용액 형태. 연구용으로만 사용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 1–2 µg/mL |
| Peptide Array (Array) | Assay-dependent |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | LGALS3/4792 |
| Immunogen | A synthetic peptide from the C-terminus of human LGALS3 protein (aa 150–200) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Galactose-specific lectin which binds IgE. May mediate with the alpha-3, beta-1 integrin the stimulation by CSPG4 of endothelial cell migration. Together with DMBT1, required for terminal differentiation of columnar epithelial cells during early embryogenesis.
In the nucleus, acts as a pre-mRNA splicing factor. Involved in acute inflammatory responses including neutrophil activation and adhesion, chemoattraction of monocytes and macrophages, opsonization of apoptotic neutrophils, and activation of mast cells.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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