Thermo Fisher Scientific Pepsinogen II Recombinant Rabbit Monoclonal Antibody (10Q1X2)
Pepsinogen II 단백질을 인식하는 recombinant rabbit monoclonal antibody. IHC(P) 및 ELISA에 사용 가능. Human, Mouse, Rat 반응성. HEK293 발현, IgG 형식, 비결합형 액상 항체. 위암 관련 연구 및 위장 질환 바이오마커 분석에 적합.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 10Q1X2 |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 1–388 of human Pepsinogen II (PG II) (NP_002621.1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 0.05% BSA, 50% glycerol |
| Contains | 0.05% ProClin 300 |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_3094271 |
Product Specific Information
Immunogen sequence:
MKWMVVVLVC LQLLEAAVVK VPLKKFKSIR ETMKEKGLLG EFLRTHKYDP AWKYRFGDLS VTYEPMAYMD AAYFGEISIG TPPQNFLVLF DTGSSNLWVP SVYCQSQACT SHSRFNPSES STYSTNGQTF SLQYGSGSLT GFFGYDTLTV QSIQVPNQEF GLSENEPGTN FVYAQFDGIM GLAYPALSVD EATTAMQGMV QEGALTSPVF SVYLSNQQGS SGGAVVFGGV DSSLYTGQIY WAPVTQELYW QIGIEEFLIG GQASGWCSEG CQAIVDTGTS LLTVPQQYMS ALLQATGAQE DEYGQFLVNC NSIQNLPSLT FIINGVEFPL PPSSYILSNN GYCTVGVEPT YLSSQNGQPL WILGDVFLRS YYSVYDLGNN RVGFATAA
Target Information
This gene encodes an aspartic proteinase belonging to the peptidase family A1. The encoded protein is a digestive enzyme produced in the stomach and is a major component of the gastric mucosa. It is also secreted into the serum and synthesized as an inactive zymogen with a basic prosegment. The enzyme becomes active at low pH through self-cleavage. Polymorphisms in this gene are associated with gastric cancer susceptibility, and serum levels serve as biomarkers for gastric diseases, including Helicobacter pylori-related gastritis. Multiple transcript variants and a pseudogene on chromosome 1 have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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