Thermo Fisher Scientific DCPS Monoclonal Antibody (OTI4H8), TrueMAB
DCPS 단백질을 인식하는 Mouse Monoclonal Antibody로 Western blot 및 IHC(P) 검증 완료. Human 반응성, 고순도 친화 크로마토그래피 정제. 동결건조 형태로 안정적이며, 연구용으로 mRNA 분해 관련 연구에 적합.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI4H8 |
| Immunogen | Full length human recombinant protein of human DCPS produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
DCPS is necessary for complete degradation of mRNAs during normal turnover and nonsense-mediated decay.
It removes the 7-methyl guanine cap structure from short mRNA fragments (<10 nucleotides) generated by 3'→5' exosome-mediated decay, releasing m7GMP.
Also degrades m7GDP to m7GMP but has no activity toward mRNA molecules longer than 25 nucleotides.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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