Thermo Fisher Scientific ADAMTS8 Monoclonal Antibody (OTI2A5), TrueMAB
인체 ADAMTS8 단백질을 인식하는 Mouse monoclonal 항체로 Western blot에 적합. HEK293T 세포에서 발현된 full-length 단백질을 면역원으로 사용. 동결건조 형태로 제공되며 PBS buffer에 8% trehalose 포함. 연구용으로만 사용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2A5 |
| Immunogen | Full length human recombinant protein of human ADAMTS8 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step (recommended: Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
The ADAMTS8 gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family.
Members share several distinct protein modules, including:
- Propeptide region
- Metalloproteinase domain
- Disintegrin-like domain
- Thrombospondin type 1 (TS) motif
This enzyme contains two C-terminal TS motifs and disrupts angiogenesis in vivo.
Several disorders, including lung neoplasms, have been mapped near this gene.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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