Thermo Fisher Scientific EPB41L2 Polyclonal Antibody
EPB41L2 단백질을 인식하는 Thermo Fisher Scientific의 Goat Polyclonal Antibody로, Western blot 및 IHC에 사용 가능. 고순도, 안정적 액상 형태이며 인간 시료 반응성. 연구용으로만 사용.
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Thermo Fisher Scientific EPB41L2 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.3 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide sequence (DYDPEEHGSID) corresponding to the internal amino acids of EPB41L2 (aa 347–358) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_11001161 |
Product Specific Information
This antibody is tested in Peptide ELISA: antibody detection limit dilution 16,000.
Target Information
The 4.1 gene family encodes a group of multifunctional cytoskeletal proteins (4.1R, 4.1G, 4.1N, and 4.1B), predominantly expressed in the nervous system.
4.1G stabilizes spectrin-actin interactions and is associated with hereditary elliptocytosis.
4.1R is essential for maintaining erythrocyte shape and membrane mechanical properties.
Both 4.1R and 4.1G are distributed in the cerebellum and modulate neuronal membrane mechanical properties by promoting fodrin/actin association.
4.1N (EPB41L1) and 4.1B (EPB41L3) are strongly expressed in the brain.
Antibodies to 4.1N detect multiple forms enriched in postsynaptic density preparations, while antibodies to 4.1B detect two forms.
Usage Note
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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