Thermo Fisher Scientific ULK2 Monoclonal Antibody (8G3)
ULK2 단백질을 표적으로 하는 마우스 단클론 항체로, Western blot 및 ELISA에 적합. 자가포식 관련 연구에 활용 가능하며, 고순도 친화 크로마토그래피 정제. -20°C에서 보관, 방부제 무첨가.
- 카탈로그번호
- H00009706-M08
- 판매단위
- pk
카탈로그
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Thermo Fisher Scientific ULK2 Monoclonal Antibody (8G3)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–5 µg/mL |
| ELISA | 0.1 ng/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG3, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 8G3 |
| Immunogen | ULK2 (AAH34988, 743–843 a.a.) 부분 재조합 단백질 (GST 태그 포함, GST MW = 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
FLRTRTTSVG PSNSGGSLCA MSGRVCVGSP PGPGFGSSPP GAEAAPSLRY VPYGASPPSL EGLITFEAPE LPEETLMERE HTDTLRHLNV MLMFTECVLD L
Target Information
ULK2 (also known as ATG1B) is a key serine/threonine protein kinase acting at the upstream step of autophagosome formation. Knockout of ULK2 results in severe autophagy defects. ULK2 is highly conserved among eukaryotes and shows high homology with ULK1. Both ULK1 and ULK2 form a complex with ATG13 and FIP200 that mediates TOR signaling essential for autophagy. ULK2 is also implicated in early neuronal growth and differentiation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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