Thermo Fisher Scientific ULK2 Monoclonal Antibody (3H8)
ULK2 단백질을 인식하는 Mouse IgG2a 형 단일클론 항체로 Western blot과 ELISA에 최적화됨. 자가포식 관련 단백질 연구에 유용하며, 고순도 친화 크로마토그래피로 정제됨. PBS(pH 7.4) 용액 형태로 제공되며, -20°C에서 보관 권장.
- 카탈로그번호
- H00009706-M09
- 판매단위
- pk
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–5 µg/mL |
| ELISA | 0.1 ng/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 3H8 |
| Immunogen | ULK2 (AAH34988, 743–843 a.a.) partial recombinant protein with GST tag (GST tag MW: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Protein Sequence:
FLRTRTTSVG PSNSGGSLCA MSGRVCVGSP PGPGFGSSPP GAEAAPSLRY VPYGASPPSL EGLITFEAPE LPEETLMERE HTDTLRHLNV MLMFTECVLD L
Target Information
ULK2 (also known as ATG1B) is a key serine/threonine protein kinase acting at the upstream step of autophagosome formation. Knockout of ULK2 results in a severe defect in the autophagy pathway. ULK2 is highly conserved among eukaryotes and shows high homology with ULK1. Both ULK1 and ULK2 form a complex with ATG13 and FIP200 that mediates TOR signaling and is essential for autophagy. ULK2 is also involved in early neuronal growth and differentiation.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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