Thermo Fisher Scientific ULK2 Monoclonal Antibody (2A12)
ULK2 단백질을 표적하는 Thermo Fisher Scientific의 단클론 항체로, 인간 시료에 반응합니다. Western blot, ICC/IF, ELISA에 적용 가능하며, GST 태그가 포함된 ULK2 부분 재조합 단백질을 면역원으로 사용했습니다. 연구용으로만 사용됩니다.
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Thermo Fisher Scientific ULK2 Monoclonal Antibody (2A12)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–5 µg/mL |
| Immunocytochemistry (ICC/IF) | 10 µg/mL |
| ELISA | 0.3 ng/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 2A12 |
| Immunogen | ULK2 (AAH34988, 743–843 a.a.) partial recombinant protein with GST tag (MW of GST tag: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
FLRTRTTSVG PSNSGGSLCA MSGRVCVGSP PGPGFGSSPP GAEAAPSLRY VPYGASPPSL EGLITFEAPE LPEETLMERE HTDTLRHLNV MLMFTECVLD L
Target Information
ULK2, also known as ATG1B, is a key serine/threonine protein kinase acting at the most upstream step of autophagosome formation. Knockout of ULK2 causes severe defects in the autophagy pathway. ULK2 is highly conserved among eukaryotes and shows high homology with ULK1. Both ULK1 and ULK2 form a complex with ATG13 and FIP200, mediating TOR signaling essential for autophagy. ULK2 is also implicated in early neuronal growth and differentiation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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