Thermo Fisher Scientific P2RY1 Polyclonal Antibody
Rabbit polyclonal antibody targeting P2RY1 receptor. Validated for IHC applications with broad species reactivity (human, mouse, rat, guinea pig). Lyophilized form, reconstitutable in sterile water. Suitable for research use in neuronal and platelet si...
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (IHC) | 1:300–1:2,000 |
Publications: 2 publications available (see references component)
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Guinea pig, Human, Mouse, Rat |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from amino acid region 323–373 of mouse P2RY1 conjugated to blue carrier protein |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4 °C for short term. For long-term storage, store at −20 °C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Reconstitute in 100 µL of sterile water.
- Centrifuge to remove any insoluble material.
- The peptide is homologous in rat and human.
- Specificity: P2RY1.
Target Information
P2Y1 is a purinergic receptor that mediates platelet shape change and aggregation by binding ADP, leading to mobilization of intracellular calcium via activation of phospholipase C. It also mediates nitric oxide release and may modulate neuronal signal transmission.
P2Y1 is expressed widely, especially in the brain, and ESTs have been isolated from human embryo, lung, and placenta libraries.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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