Thermo Fisher Scientific PDLIM7 Polyclonal Antibody
Human PDLIM7 단백질을 인식하는 Rabbit Polyclonal Antibody로, WB, IHC(P), ICC/IF에 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, PBS 버퍼에 40% 글리세롤과 0.02% sodium azide 포함. 연구용으로만 사용.
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- PA553846
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human PDLIM7. Recombinant protein control fragment (Product #RP-92315). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2645341 |
Product Specific Information
Immunogen sequence:
HLTGTEFMQD PDEEHLKKSS QVPRTEAPAP ASSTPQEPWP GPTAPSPTSR PPWAVDPAFA ERYAPDKTST VLTR
Highest antigen sequence identity to the following orthologs:
- Mouse: 92%
- Rat: 92%
Target Information
The protein encoded by this gene belongs to a family of proteins containing conserved PDZ and LIM domains. LIM domains are involved in protein-protein interactions related to gene transcription, development, and cytoskeletal organization.
The LIM domains bind to protein kinases, while the PDZ domain associates with actin filaments.
This gene product participates in assembling an actin filament-associated complex essential for ret/ptc2 mitogenic signaling. It likely functions as an adapter, localizing LIM-binding proteins to actin filaments in skeletal and nonmuscle tissues.
Alternative splicing produces multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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