Thermo Fisher Scientific MYL9/MYL12 Polyclonal Antibody
MYL9/MYL12 단백질을 인식하는 Rabbit Polyclonal Antibody로, Western blot 및 Immunocytochemistry에 사용 가능. Human, Mouse, Rat 반응성. 20 kDa 밴드 검출. Affinity chromatography 정제, PBS/BSA/glycerol buffer에 보관. 연구용 전용.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | MLC synthetic peptide (coupled to KLH) corresponds to amino acid residues in the N-terminus of human myosin regulatory light chain 12A (Myl12A). This peptide sequence is highly conserved in human, rat, mouse, chicken, and zebrafish Myl12A, and in other smooth muscle and non-muscle MLCs. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1 mg/mL BSA, 50% glycerol |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2942953 |
Product Specific Information
The antibody detects a 20 kDa band corresponding to the molecular weight of myosin light chain in mouse C2C12, rat PC12, and human A431.
Target Information
Myosin regulatory light polypeptide 9 (MYL9) is a highly conserved, ubiquitously expressed protein encoded by the MYL9 gene in humans. Myosin, a structural component of muscle, is composed of two heavy chains and four light chains, including phosphorylatable and nonphosphorylatable subunits. MYL9 may regulate muscle contraction by modulating the ATPase activity of myosin heads. MYL9 and MYL12 are functional ligands for CD69, and blockade of CD69–MYL9/12 interaction ameliorates allergic airway inflammation in mouse models of asthma.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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