Thermo Fisher Scientific GFER Polyclonal Antibody
Thermo Fisher Scientific의 GFER Polyclonal Antibody는 인간 GFER 단백질을 인식하는 토끼 유래 IgG 항체입니다. 면역세포화학(ICC/IF)에 적합하며, 항원 친화 크로마토그래피로 정제되었습니다. 액상 형태로 제공되며 장기 보관 시 -20°C에서 안정적으로 유지됩니다.
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Applications
Immunocytochemistry (ICC/IF)
- Tested Dilution: 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human GFER. Recombinant protein control fragment (Product #RP-107251) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C and avoid freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2662999 |
Product Specific Information
Immunogen sequence:
RFHGGNLFFLP GGARSEMMDD LATD
Highest antigen sequence identity to orthologs:
- Mouse: 64%
- Rat: 60%
Target Information
Isoform 1: FAD-dependent sulfhydryl oxidase that regenerates the redox-active disulfide bonds in CHCHD4/MIA40, a chaperone essential for disulfide bond formation and protein folding in the mitochondrial intermembrane space.
The reduced form of CHCHD4/MIA40 forms a transient intermolecular disulfide bridge with GFER/ERV1, resulting in regeneration of the essential disulfide bonds in CHCHD4/MIA40, while GFER/ERV1 becomes re-oxidized by donating electrons to cytochrome c or molecular oxygen.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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