Thermo Fisher Scientific F13A1 Monoclonal Antibody (OTI3F1), TrueMAB

Applications

ELISA (ELISA)

• Tested Dilution: 1:100–1:1,000

Luminex (LUM)

• Tested Dilution: 1:100–1:1,000

Product Specifications

Additional Formats

• Biotin
• Request custom conjugation

Target Information

This gene encodes the coagulation factor XIII A subunit. Coagulation factor XIII is the last zymogen to become activated in the blood coagulation cascade. Plasma factor XIII is a heterotetramer composed of two A subunits and two B subunits. The A subunits have catalytic function, while the B subunits serve as plasma carrier molecules. Platelet factor XIII consists only of two A subunits identical to those of plasma origin. Upon activation by thrombin and calcium ions, plasma factor XIII dissociates its B subunits and yields the active enzyme factor XIIIa. This enzyme catalyzes crosslinking between fibrin molecules, stabilizing the fibrin clot, and also crosslinks alpha-2-plasmin inhibitor or fibronectin to fibrin. Factor XIII deficiency can cause bleeding tendency, defective wound healing, and habitual abortion.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.