Thermo Fisher Scientific Nodal Polyclonal Antibody
Thermo Fisher Scientific의 Nodal Polyclonal Antibody는 인간 및 생쥐 시료에서 NODAL 단백질 검출에 적합한 고품질 항체입니다. Western blot과 ICC/IF에 사용 가능하며, 항원 친화 크로마토그래피로 정제되었습니다. 연구용으로만 사용됩니다.
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Applications
- Western Blot (WB): 1:500
- Immunocytochemistry (ICC/IF): 1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to the C-terminal region of human NODAL (residues 200–347) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.32 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 50% glycerol, 0.1% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term; for long term, store at -20°C. Avoid freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11153040 |
Product Specific Information
The target sequence shows 98% sequence homology with rat.
Target Information
NODAL is a key member of the TGF-beta family involved in cellular differentiation. It is expressed in many developing tissues and is associated with various cancers. NODAL expression is regulated by the Notch signaling pathway, which influences metastatic behavior, particularly in melanoma. The level of NODAL expression can help determine cancer stage and progression. Interactions between NODAL and Cripto contribute to tumor development, and overexpression is linked to preeclamptic placenta.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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