Thermo Fisher Scientific METTL3 Recombinant Rabbit Monoclonal Antibody (ARC0487)
METTL3 단백질을 인식하는 재조합 토끼 단클론 항체로, Western blot, ICC/IF, ELISA, IP 등 다양한 응용에 적합합니다. HEK293 세포에서 발현되었으며, 높은 특이성과 재현성을 제공합니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:100–1:400 |
| ELISA | 1 µg/mL |
| Immunoprecipitation (IP) | 0.5–4 µg antibody for 200–400 µg extracts |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | ARC0487 |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 2–250 of human METTL3 (Q86U44) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol, 0.05% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | –20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2849151 |
Product Specific Information
Immunogen sequence:
SDTWSSIQAH KKQLDSLRER LQRRRKQDSG HLDLRNPEAA LSPTFRSDSP VPTAPTSGGP KPSTASAVPE LATDPELEKK LLHHLSDLAL TLPTDAVSIC LAISTPDAPA TQDGVESLLQ KFAAQELIEV KRGLLQDDAH PTLVTYADHS KLSAMMGAVA EKKGPGEVAG TVTGQKRRAE QDSTTVAAFA SSLVSGLNSS ASEPAKEPAK KSRKHAASDV DLEIESLLNQ QSTKEQQSKK VSQEILELL
Target Information
METTL3 is the 70 kDa subunit of MT-A, which is part of N6-adenosine-methyltransferase.
This enzyme is involved in the posttranscriptional methylation of internal adenosine residues in eukaryotic mRNAs, forming N6-methyladenosine.
For Research Use Only. Not for use in diagnostic procedures.
Not for resale without express authorization.
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