
Thermo Fisher Scientific CTLA-4 Monoclonal Antibody (1B8), FITC
FITC 결합된 CTLA-4 단클론 항체(1B8)는 마우스 시료에서 CTLA-4 검출에 적합합니다. Flow Cytometry, ELISA, Neutralization 등 다양한 응용 가능. 고순도 정제, 안정적 형광 특성(Ex/Em 498/517 nm), 연구용 전용 시약.
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Flow Cytometry (Flow) | 0.1–0.2 µg / 1×10⁶ cells | View 3 publications |
| ELISA | 3 µg / 1×10⁶ cells | View publications |
| Neutralization | – | View 1 publication |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Mouse |
| Published Species | Mouse |
| Host / Isotype | Armenian hamster / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 1B8 |
| Immunogen | Mouse CD152 (CTLA-4), extracellular portion fused to murine IgG2a |
| Conjugate | FITC |
| Excitation / Emission Max | 498 / 517 nm |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Purified |
| Storage Buffer | PBS, pH 7.4 |
| Contains | <0.1% sodium azide |
| Storage Conditions | 4°C, store in dark |
| Shipping Conditions | Wet ice (domestic); Wet or Dry ice (international) |
| RRID | AB_2536593 |
Additional Formats
- PE conjugate available (PE format)
- Custom conjugation requests available (Request form)
Target Information
CTLA4 (Cytotoxic T-Lymphocyte Antigen 4) is a CD28-family receptor mainly expressed on CD4⁺ T cells. It binds the same ligands as CD28 (CD80 and CD86 on B cells and dendritic cells) but with higher affinity. Unlike CD28, which enhances T cell activation, CTLA4 inhibits T cell function. Intracellular CTLA4 is also found in regulatory T cells and may be critical for their activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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