Thermo Fisher Scientific ZFYVE19 Polyclonal Antibody
ZFYVE19 단백질을 표적으로 하는 Thermo Fisher Scientific의 Rabbit Polyclonal 항체. Western blot 및 Immunoprecipitation에 적합. 1 mg/mL 농도의 액상 형태로 제공되며, 4°C에서 보관. 세포질분열 조절 연구에 활용 가능.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:5,000 |
| Immunoprecipitation (IP) | 2–5 µg/mg lysate |
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 425 and 471 of Human zinc finger, FYVE domain containing 19 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Target Information
Key regulator of the abscission step in cytokinesis: part of the cytokinesis checkpoint, a process required to delay abscission to prevent premature resolution of intercellular chromosome bridges and accumulation of DNA damage. Together with CHMP4C, it retains abscission-competent VPS4 (VPS4A and/or VPS4B) at the midbody ring until checkpoint signaling is terminated at late cytokinesis. Deactivation of AURKB results in dephosphorylation of CHMP4C, followed by its dissociation from ZFYVE19/ANCHR and VPS4, leading to abscission.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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