Thermo Fisher Scientific p73 Monoclonal Antibody (5B429)
Human, Mouse, Rat 반응성의 p73 단클론 항체로 다양한 면역분석(WB, IHC, ICC, Flow, IP, ChIP)에 사용 가능. N-말단 영역을 인식하며 Protein G로 정제된 액상 형태. 연구용으로 DNA 손상 관련 세포사멸 연구에 적합.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 2 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 5–15 µg/mL |
| Immunohistochemistry (Frozen) (IHC (F)) | 5–15 µg/mL |
| Immunocytochemistry (ICC/IF) | 1:10–1:500 |
| Flow Cytometry (Flow) | 1 µg/mL |
| Immunoprecipitation (IP) | 1:10–1:500 |
| ChIP assay (ChIP) | 1:20–1:1,000 |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 5B429 |
| Immunogen | This antibody was raised against full-length human p73. It reacts with an epitope located on the N-terminal region of human p73. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.0 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2537686 |
Target Information
P73 (TP73) participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, while isoforms lacking the domain are anti-apoptotic and inhibit the function of p53 and transactivating p73 isoforms. It may function as a tumor suppressor protein.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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