
Thermo Fisher Scientific PDE1C Polyclonal Antibody
Human PDE1C 단백질에 특이적인 Rabbit Polyclonal 항체로, IHC(P) 및 ICC/IF에 최적화됨. 항원 친화 크로마토그래피로 정제된 액상 항체이며, 0.1 mg/mL 농도로 PBS(40% 글리세롤) 버퍼에 보존. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human PDE1C. Recombinant protein control fragment (Product # RP-103120) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2645326 |
Product Specific Information
Immunogen sequence:
EEQQKEMEAK SQAEEGASGK AEKKTSGETK NQVNGTRANK SDNPRGKNSK AEKSSGEQQQ NGDFKDGK
Highest antigen sequence identity to the following orthologs:
- Mouse – 76%
- Rat – 78%
Target Information
Cyclic nucleotide phosphodiesterases (PDEs) catalyze hydrolysis of the cyclic nucleotides cAMP and cGMP to the corresponding nucleoside 5′-monophosphates. Mammalian PDEs are classified into several families based on biochemical properties. Members of the PDE1 family, such as PDE1C, are calmodulin-dependent PDEs (CaM-PDEs) that are stimulated by a calcium–calmodulin complex (Repaske et al., 1992).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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