Thermo Fisher Scientific CD1a Monoclonal Antibody (NA1/34-HLK)

Applications

Immunohistochemistry (Frozen) (IHC (F))

• Assay-dependent

Immunocytochemistry (ICC/IF)

• Assay-dependent

Flow Cytometry (Flow)

• 1:50–1:100

Product Specifications

Additional Formats

• FITC
• PE
• Request custom conjugation

Product Specific Information

For FACS analysis, use 10 µL of the suggested working dilution to label 1×10^6 cells in 100 µL.
A suggested positive control for immunohistochemical applications is skin.

Target Information

CD1a is a non-polymorphic MHC Class I-related cell surface glycoprotein expressed in association with β2-microglobulin.
It is found on cortical thymocytes, Langerhans cells, dendritic cells, and certain T-cell leukemias.
CD1a mediates presentation of lipid and glycolipid antigens to T cells.
The human genome contains five CD1 family genes (CD1a, b, c, d, e) located on chromosome 1.
CD1a localizes to the plasma membrane and early endocytic vesicles.
Alternative spliced transcript variants have been observed but their biological validity is undetermined.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.