Thermo Fisher Scientific MCD Polyclonal Antibody
Thermo Fisher Scientific의 MCD Polyclonal Antibody는 인간 및 마우스 시료에 반응하며, Western blot, IHC, ICC/IF에 적합합니다. Rabbit IgG 기반 비결합 항체로, 항원 친화 크로마토그래피로 정제되었습니다. 지방산 산화 연구 및 MCD 단백질 분석에 활용됩니다.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:3,000 | View 3 publications |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:1,000 | - |
| Immunocytochemistry (ICC/IF) | 1:100–1:1,000 | - |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Published Species | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to amino acids 90–304 of MCD (Uniprot ID#O95822) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 20% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_11154499 |
Product Specific Information
- Recommended positive controls: 293T, A431, HeLa, HepG2, C8D30
- Predicted reactivity: Mouse (95%), Rat (93%), Bovine (88%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
MCD catalyzes the breakdown of malonyl-CoA to acetyl-CoA and carbon dioxide. Malonyl-CoA is an intermediate in fatty acid biosynthesis and inhibits the transport of fatty acyl CoAs into mitochondria. Consequently, MCD increases the rate of fatty acid oxidation. It is localized in mitochondria, peroxisomes, and cytoplasm. Mutations in this gene result in malonyl-CoA decarboxylase deficiency.
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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(이미지 파일명: PA5-22081_MCD_O95822-1_Rabbit_PDP.jpeg)
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