Thermo Fisher Scientific Carboxypeptidase A1 Monoclonal Antibody (OTI2A3)
Carboxypeptidase A1 단백질을 인식하는 Mouse Monoclonal Antibody (Clone OTI2A3). Western blot, IHC(P), ICC/IF에 적합. 인간 시료 반응성. Affinity Chromatography로 정제된 액상형 항체로, 장기 보관 시 -20°C에서 보관 권장.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50 |
| Immunocytochemistry (ICC/IF) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2A3 |
| Immunogen | Recombinant protein expressed in E. coli corresponding to amino acids 1–419 of CPA1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.32 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2722914 |
Target Information
CPA1 (Carboxypeptidase A1)
CPA1, also known as CPA, is a 419 amino acid secreted monomeric protein highly expressed in pancreatic tissue. It functions as a zinc-dependent pancreatic exopeptidase that catalyzes the release of C-terminal amino acids from proteins, playing a key role in protein digestion and degradation. CPA1 activity is also implicated in zymogen inhibition, potentially regulating enzyme activation pathways. Abnormal CPA1 levels are associated with pancreatic cancer, suggesting roles in tumor progression or suppression.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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