Thermo Fisher Scientific PCDH1 Monoclonal Antibody (4H2)
PCDH1 단백질을 인식하는 Mouse monoclonal antibody. Western blot과 ELISA에 사용 가능하며, 인간 시료에 반응. Affinity chromatography로 정제된 액상 형태로 제공되며, 보존제 무첨가 PBS 용액에 담김. 연구용으로만 사용.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–5 µg/mL |
| ELISA | 0.3 ng/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 4H2 |
| Immunogen | PCDH1 (NP_002578, 62 a.a. ~169 a.a) partial recombinant protein with GST tag (MW of GST tag: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Protein Sequence:
YKVPEEQPPN TLIGSLAADY GFPDVGHLYK LEVGAPYLRV DGKTGDIFTT ETSIDREGLR ECQNQLPGDP CILEFEVSIT DLVQNGSPRL LEGQIEVQDI NDNTPNFA
Target Information
Protocadherin 1 (PCDH1), also known as cadherin-like protein 1, is a transmembrane protein involved in cell-cell adhesion. It belongs to the delta1-protocadherin family, which includes protocadherin-1, -7, -9, and -11(X/Y). These proteins have seven extracellular cadherin repeats, a transmembrane domain, and a cytoplasmic domain, existing in both short and long isoforms.
PCDH1 expression is temporally and spatially regulated, playing roles in early development and mature tissues. In mice, it is expressed in the brain, spinal cord, peripheral ganglia, inner ear, hair follicles, kidney, reproductive organs, prostate, and seminal gland.
PCDH1 is a susceptibility gene for bronchial hyperresponsiveness in humans and is also expressed on human pluripotent stem cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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