Thermo Fisher Scientific PCDHGC3 Monoclonal Antibody (3A1)
인간 PCDHGC3 단백질을 인식하는 mouse monoclonal antibody. Western blot과 ELISA에 사용 가능. Affinity chromatography로 정제된 액상 항체로, PBS(pH 7.4) buffer에 보존제 없이 제공. -20°C에서 보관하며 freeze/thaw cycle은 피해야 함.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–5 µg/mL |
| ELISA | 0.1 ng/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 3A1 |
| Immunogen | PCDHGC3 (NP_002579, 71 a.a. ~178 a.a.) partial recombinant protein with GST tag (GST tag MW: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Protein Sequence:
GASRRFFEVN RETGEMFVND RLDREELCGT LPSCTVTLEL VVENPLELFS VEVVIQDIND NNPAFPTQEM KLEISEAVAP GTRFPLESAH DPDVGSNSLQ TYELSRNE
Target Information
This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome 5. These clusters have an immunoglobulin-like organization, suggesting a novel mechanism of regulation and expression.
The gamma cluster includes 22 genes divided into three subfamilies:
- Subfamily A: 12 genes
- Subfamily B: 7 genes + 2 pseudogenes
- Subfamily C: 3 genes
Each variable region exon encodes the extracellular region (6 cadherin ectodomains + transmembrane region), while constant region exons encode the shared cytoplasmic domain. These neural cadherin-like cell adhesion proteins play critical roles in brain-specific cell-cell connections. Alternative splicing has been described for the gamma cluster genes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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