Thermo Fisher Scientific ATOH1 Polyclonal Antibody
ATOH1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot, ICC/IF, ChIP 등 다양한 응용에 적합. 인간, 생쥐, 랫드 반응성. 항원 친화 크로마토그래피로 정제되어 높은 특이성과 안정성 제공.
- 판매단위
- pk
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:3,000 | View 1 publication |
| Immunocytochemistry (ICC/IF) | 1:100–1:1,000 | - |
| ChIP assay (ChIP) | - | View 1 publication |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to a region within amino acids 285–354 of Human MATH1 (ATOH1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.42 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 20% glycerol |
| Contains | 0.025% ProClin 300 |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2546868 |
Product Specific Information
Predicted reactivity: Mouse (100%), Rat (100%), Chimpanzee (100%), Bovine (100%)
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
The Drosophila atonal gene produces a protein with basic helix-loop-helix (bHLH) domains that play an essential role in the development of the Drosophila nervous system.
Mammalian atonal homolog 1 (MATH-1), also known as Atoh1, Ath1, or HATH-1, is a 351 amino acid transcription factor with a bHLH domain homologous to the Drosophila proneural gene atonal.
In mice, MATH-1 expression begins by embryonic day 9.5, initially localizing to cranial ganglia and the dorsal CNS. By day 18, expression becomes restricted to the external granular layer of the cerebellum and is undetectable in adults.
It is suggested that MATH-1 may play a role in the differentiation of neural cell subsets by activating E box-dependent transcription.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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