Thermo Fisher Scientific KV1.1 (KCNA1) Polyclonal Antibody

Applications and Tested Dilution

Product Specifications

Product Specific Information

• Shipped at room temperature as a lyophilized powder.
• Store at -20°C upon receipt.
• Reconstitute using 50 µL deionized water.

Target Information

This gene encodes a voltage-gated delayed potassium channel related to the Drosophila Shaker channel. The protein has six transmembrane segments, with the S5–S6 loop forming the pore and containing the conserved selectivity filter motif. The functional channel is a homotetramer.
The N-terminus associates with beta subunits that modify inactivation properties and expression levels, while the C-terminus interacts with a PDZ domain protein responsible for channel targeting.
Mutations in this gene have been associated with myokymia with periodic ataxia.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.