Thermo Fisher Scientific BRWD2 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:1,000-1:2,000

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 975-1224 of human WDR11 (NP_0605878) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:BRWD2,uniProtId:Q9BZH6-1,ncbiNodeId:9606,antigenRange:975-1224,antigenLength:1224,antigenImageFileName:PA5-88006_BRWD2_Q9BZH6-1_Rabbit.svg,antigenImageFileNamePDP:PA5-88006_BRWD2_Q9BZH6-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

2.78 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2804582

Product Specific Information

Immunogen sequence: YFQKFQLERV NLQEVKRSTY DHTRKCTDQL LLLGQTDRAV QLLLETSADN QHYYCDSLKA CLVTTVTSSG PSQSTIKLVA TNMIANGKLA EGVQLLCLID KAADACRYLQ TYGEWNRAAW LAKVRLNPEE CADVLRRWVD HLCSPQVNQK SKALLVLLSL GCFFSVAETL HSMRYFDRAA LFVEACLKYG AFEVTEDTEK LITAIYADYA RSLKNLGFKQ GAVLFASKAG AAGKDLLNEL ESPKEEPIEE; Positive Samples: DU145, HL-60, HepG2; Cellular Location: Cytoplasm, Membrane, Nucleus, Single-pass membrane protein

Target Information

WDR11 is a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This gene is located in the chromosome 10q25-26 region, which is frequently deleted in gliomas and tumors of other tissues, and is disrupted by the t(10;19) translocation rearrangement in glioblastoma cells. The gene location suggests that it is a candidate gene for the tumor suppressor locus.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.