Thermo Fisher Scientific Ly-6G Monoclonal Antibody (1A8-Ly6g), FITC, eBioscience
마우스 Ly-6G(Gr-1) 항원을 인식하는 단클론 항체로, 중성구 특이적 결합을 통해 세포 분석 및 면역염색에 활용. FITC 형광 표지로 488 nm 청색 레이저에서 검출 가능. Flow cytometry 등 다양한 응용 가능. 4°C 암소 보관.
- 카탈로그번호
- 11-9668-8x (2개 옵션)
- 판매단위
- pk
카탈로그
2개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific Ly-6G Monoclonal Antibody (1A8-Ly6g), FITC, eBioscience
Thermo Fisher Scientific Ly-6G Monoclonal Antibody (1A8-Ly6g), FITC, eBioscience
Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Immunohistochemistry (IHC) | - | View 5 publications |
| Immunohistochemistry (Paraffin) (IHC (P)) | - | View 1 publication |
| Immunohistochemistry (Frozen) (IHC (F)) | - | View 1 publication |
| Immunocytochemistry (ICC/IF) | - | View 4 publications |
| Flow Cytometry (Flow) | 0.5 µg/test | View 59 publications |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Published Species | Mouse |
| Host / Isotype | Rat / IgG2a, kappa |
| Recommended Isotype Control | Rat IgG2a kappa Isotype Control (eBR2a), FITC, eBioscience™ |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 1A8-Ly6g |
| Conjugate | FITC |
| Excitation / Emission Max | 498 / 517 nm |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.2 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C, store in dark, DO NOT FREEZE |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2572531 |
Available Formats
- Alexa Fluor 700
- APC
- APC-eFluor 780
- Biotin
- Brilliant UV 395
- Brilliant UV 563
- Brilliant UV 661
- Brilliant UV 737
- Brilliant Violet 421
- Brilliant Violet 480
- Brilliant Violet 650
- Brilliant Violet 786
- eFluor 450
- Functional Grade
- PE
- PE-Cyanine5
- PE-Cyanine7
- PE-eFluor 610
- PerCP-eFluor 710
- Super Bright 436
- Super Bright 600
- Super Bright 702
- Request custom conjugation available
Product Specific Information
The monoclonal antibody 1A8-Ly6g reacts with mouse Ly-6G (Gr-1), a 25-kDa GPI protein expressed exclusively by neutrophils. Ly-6G is associated with neutrophil infiltration, recruitment, and migration, and interacts with B2 integrins CD11a and CD11b.
Unlike RB6-8C5, 1A8-Ly6g binds specifically to Ly-6G on neutrophils and can be used to deplete neutrophils, showing antagonist activity.
Applications Reported: Flow cytometric analysis.
Applications Tested: Flow cytometric analysis of mouse splenocytes (≤0.5 µg/test).
A test is defined as staining a cell sample in 100 µL volume (10⁵–10⁸ cells/test).
Careful titration recommended for optimal performance.
Excitation: 488 nm
Emission: 520 nm
Laser: Blue Laser
Filtration: 0.2 µm post-manufacturing filtered
Target Information
Ly6G (Lymphocyte antigen 6 complex locus G6D) is part of the myeloid differentiation antigen Gr-1, together with Ly6C.
Ly6G (21–25 kDa) is expressed by myeloid-derived cells in bone marrow and serves as a marker for neutrophils, monocytes, and granulocytes.
Expression correlates with granulocyte differentiation and maturation.
Studies indicate Ly6G involvement in anti-tumor response and inhibitory effects on local immune responses.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.