Thermo Fisher Scientific ZRANB2 Polyclonal Antibody
ZRANB2 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal 항체로, WB 및 IHC(P) 실험에 적합. 인간, 생쥐, 랫트 반응성. 항원 친화 크로마토그래피로 정제되었으며, 고순도(>95%) 및 37 kDa 단백질 검출 가능. 연구용 전용 제품.
- 카탈로그번호
- PA536139
- 판매단위
- pk
카탈로그
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Thermo Fisher Scientific ZRANB2 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 121–170 of human ZRANB2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2553386 |
Product Specific Information
- Detects endogenous protein at a molecular weight of 37 kDa
- Purity is >95% by SDS-PAGE
Target Information
Zinc-finger proteins contain DNA-binding domains and play diverse roles in transcriptional regulation.
ZNF265 (also known as ZRANB2, ZIS, ZIS1, or ZIS2) is a 330 amino acid protein belonging to the ZRANB2 family.
Localized to the nucleus, ZNF265 functions as a splicing factor responsible for alternative splicing of Tra-2 beta transcripts and may interfere with constitutive 5′-splice selection.
It contains two RanBP2-type zinc fingers that mediate RNA-binding activity.
Two isoforms (ZIS-1 and ZIS-2) are expressed due to alternative splicing events. Upon DNA damage, ZIS-2 may be phosphorylated by ATM or ATR.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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