Thermo Fisher Scientific ABCG1 Polyclonal Antibody
ABCG1 단백질을 인식하는 Rabbit Polyclonal 항체로 Western blot에 적합합니다. Human, Mouse, Rat에서 반응하며, 항원 친화 크로마토그래피로 정제되었습니다. PBS/glycerol buffer에 보관되며, 연구용으로만 사용 가능합니다.
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Applications
- Western Blot (WB): 1:500–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 633–678 of Human ABCG1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2719209 |
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity chromatography using an epitope-specific immunogen. The purity is greater than 95% (by SDS-PAGE).
Target Information
ATP-binding cassette (ABC) transporter genes regulate dietary cholesterol retention in the body. The ABC transporter ABCG1 (ABC8) is expressed on the cell surface and in intracellular compartments of cholesterol-laden macrophages. Its expression is induced in monocyte-derived macrophages during cholesterol influx mediated by acetylated low-density lipoprotein (LDL). Conversely, lipid efflux mediated by HDL(3) suppresses ABCG1 expression in cholesterol-laden macrophages.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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