Thermo Fisher Scientific AMOTL1 Polyclonal Antibody
Human AMOTL1 단백질을 인식하는 Rabbit Polyclonal 항체로, IHC(P) 및 ICC/IF에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, PBS(glycerol 포함) 용액 형태로 제공됩니다. 세포 극성 및 밀착연접 연구에 활용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:500 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human AMOTL1. Recombinant protein control fragment (Product # RP-94762) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2637915 |
Product Specific Information
Immunogen sequence:
SPSACYSPSS PVQVLEDSTY FSPDFQLYSG RHETSALTVE ATSSIREKVV EDPLCNFHSP NFLRISEVEM RGSEDAAAGT VLQRLIQEQL RYGTPTENMN LLAIQHQATG SAGPAHPTNN FSSTENLTQE DPQMVYQSAR QEPQGQEHQV
Antigen sequence identity:
- Mouse: 82%
- Rat: 32%
Target Information
The protein encoded by this gene is a peripheral membrane protein that is a component of tight junctions (TJs). TJs form an apical junctional structure and act to control paracellular permeability and maintain cell polarity. This protein is related to angiomotin, an angiostatin binding protein that regulates endothelial cell migration and capillary formation. Two transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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