Thermo Fisher Scientific STX17 Polyclonal Antibody
Rabbit polyclonal antibody against human STX17. Validated for WB and IHC-P applications. Antigen affinity purified, supplied in PBS with 40% glycerol. For research use only.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:200–1:500 |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human STX17. Recombinant protein control fragment (Product # RP-96776) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2648055 |
Product Specific Information
Immunogen sequence:
RLEPAIQKFI KIVIPTDLER LRKHQINIEK YQRCRIWDKL HEEHINAGRT VQQLRSNIRE IEKLCLKVRK DDLVLLKRMI DPVKEEASAA TAEFLQLHLE SVEELKKQFN DEETLLQPPL TRSMTVGGAF HTTEAEASSQ SLTQ
Highest antigen sequence identity to the following orthologs:
- Mouse: 90%
- Rat: 86%
Target Information
SNAREs (soluble N-ethylmaleimide-sensitive factor-attachment protein receptors) are essential proteins for cellular membrane fusion. SNAREs on opposing membranes assemble to form a trans-SNARE complex, an extended, parallel four alpha-helical bundle that drives membrane fusion.
STX17 is a SNARE of the autophagosome involved in autophagy through direct control of autophagosome membrane fusion with the lysosome membrane. STX17 may also play a role in the early secretory pathway, maintaining the architecture of the endoplasmic reticulum-Golgi intermediate compartment (ERGIC) and Golgi, and/or regulating transport between these organelles. (Uniprot)
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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