Thermo Fisher Scientific ErbB2 (HER-2) Monoclonal Antibody (CB11)
HER2/ErbB2 단백질을 표적하는 CB11 클론의 단일클론 항체로, Western blot, IHC, ICC 등 다양한 응용 가능. 인간, 고양이, 생쥐 시료에 적합하며, 비결합형 액상 형태로 제공. 연구용으로만 사용 가능.
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Thermo Fisher Scientific ErbB2 (HER-2) Monoclonal Antibody (CB11)
Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:1,000 | View 7 publications |
| Immunohistochemistry (IHC) | - | View 24 publications |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:40 | View 3 publications |
| Immunocytochemistry (ICC/IF) | 1:100 | View 6 publications |
| Miscellaneous PubMed (Misc) | - | View 7 publications |
Product Specifications
| Specification | Description |
|---|---|
| Published species | Cat, Human, Mouse |
| Host/Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | CB11 |
| Immunogen | Synthetic internal domain of the C-erbB-2 oncoprotein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | Not Determined |
| Storage conditions | 4°C |
| Shipping conditions | Wet ice |
| RRID | AB_1073585 |
Product Specific Information
Specific binding has been demonstrated by immunoprecipitation with c-erbB-2 oncoprotein from SKBr3 cells. A positive control of breast adenocarcinoma is recommended.
Target Information
ErbB2 (HER2) is a receptor tyrosine kinase that is overexpressed in some breast tumors. Herceptin, used in treatment of metastatic Her2-positive cancer, is a monoclonal antibody targeting this kinase.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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