Thermo Fisher Scientific DAP5 Polyclonal Antibody
DAP5 단백질을 인식하는 Rabbit Polyclonal Antibody로 Western blot, IHC, ICC, ELISA, IP에 사용 가능. Human, Mouse, Rat 반응성. Affinity Chromatography로 정제된 액상 제품이며, -20°C 보관. 연구용으로만 사용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1 µg/mL |
| Immunoprecipitation (IP) | 0.5 µg–4 µg antibody for 200 µg–400 µg extracts |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 320–490 of human EIF4G2/p97 (NP_001409.3) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.26 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2914413 |
Product Specific Information
- Positive test controls include: HeLa, 293T, Jurkat, LO2, Mouse brain.
- Immunogen sequence:
PKTINQIRQD AVKDLGVFIP APMAQGMRSD FFLEGPFMPP RMKMDRDPLG GLADMFGQMP GSGIGTGPGV IQDRFSPTMG RHRSNQLFNG HGGHIMPPTQ SQFGEMGGKF MKSQGLSQLY HNQSQGLLSQ LQGQSKDMPP RFSKKGQLNA DEISLRPAQS FLMNKNQVPK L
Target Information
CDK5RAP2 is a regulator of CDK5 (cyclin-dependent kinase 5) activity.
The protein is localized to the centrosome and Golgi complex and interacts with CDK5R1 and pericentrin (PCNT).
CDK5RAP2 plays a role in centriole engagement and microtubule nucleation, and has been linked to primary microcephaly and Alzheimer’s disease.
Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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