Thermo Fisher Scientific QPRT Monoclonal Antibody (OTI4E6), TrueMAB
인간 QPRT 단백질을 인식하는 Mouse IgG1 단일클론 항체. WB, IHC(P), Flow Cytometry에 사용 가능. 동결건조 형태로 제공되며, 보존제 무첨가 PBS 버퍼에 용해. 신경퇴행성 질환 연구 등 QPRT 관련 연구용에 적합.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
| Flow Cytometry (Flow) | 1:100 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI4E6 |
| Immunogen | Full length human recombinant protein of human QPRT produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional round of desalting using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
QPRT gene encodes a key enzyme in the catabolism of quinolinate, an intermediate in the tryptophan–nicotinamide adenine dinucleotide pathway.
Quinolinate acts as a potent endogenous excitotoxin to neurons. Elevated quinolinate levels in the brain are associated with neurodegenerative disorders such as epilepsy, Alzheimer’s disease, and Huntington’s disease.
Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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