Thermo Fisher Scientific HES5 Polyclonal Antibody
HES5 단백질을 인식하는 Rabbit Polyclonal 항체로 Western blot에 적합합니다. 인간 시료에 반응하며, Affinity chromatography로 정제되었습니다. PBS 버퍼에 0.09% sodium azide가 포함되어 있으며, -20°C에서 보관합니다. 연구용으로만 사용 가능합니다.
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Applications
- Western Blot (WB): 0.2–1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the middle region of human HES5 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Wet ice |
| RRID | AB_2884445 |
Product Specific Information
- Immunogen sequence: AASDTQMKLL YHFQRPPAAP AAPAKEPKAP GAAPPPALSA KATAAAAAAH
- Storage guidance: For short term use, store at 2–8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
- Predicted homology: Cow 93%; Dog 100%; Guinea Pig 85%; Human 100%; Mouse 88%; Rat 93%
Target Information
Hairy and Enhancer-of-split homologues 5 (HES5) is a helix-loop-helix transcription factor that negatively regulates cell differentiation during embryogenesis. It contains one basic helix-loop-helix (bHLH) domain and one Orange domain. HES5 acts as a downstream effector of the Notch signaling pathway and is expressed in advanced ovarian serous adenocarcinomas and cervical squamous carcinoma. It is also reported to be abundantly expressed in osteoarthritis along with Notch1 and Jagged1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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