Thermo Fisher Scientific FMRP Polyclonal Antibody
FMRP 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, WB 및 ICC/IF에 적합합니다. Mouse 시료에 반응하며, 고순도 항원 친화 크로마토그래피로 정제되었습니다. 연구용으로만 사용되며, 안정적인 액상 형태로 제공됩니다.
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Thermo Fisher Scientific FMRP Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:3,000 |
| Immunocytochemistry (ICC/IF) | 1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Carrier-protein conjugated synthetic peptide encompassing a sequence within the center region of mouse FMRP (exact sequence proprietary) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.69 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 20% glycerol |
| Contains | 0.025% ProClin 300 |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2902057 |
Product Specific Information
- Centrifuge briefly prior to opening.
Target Information
FMR1 binds RNA and is associated with polysomes. The protein may be involved in mRNA trafficking from the nucleus to the cytoplasm. A trinucleotide repeat in the 5′ UTR is normally found at 6–53 copies, but an expansion to 55–230 repeats causes fragile X syndrome. Expansion of this repeat may also lead to one form of premature ovarian failure. Multiple alternatively spliced transcript variants encoding different protein isoforms located in distinct cellular compartments have been described for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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