Thermo Fisher Scientific PTCH2 Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 1:500–1:1,000

Product Specifications

Product Specific Information

• PA1-4135 detects Patched 2 (PTCH2) in human and mouse samples.
• Successfully used in Western blot procedures.
• Detects a ~158 kDa protein representing PTCH2 in fetal brain lysate.
• Immunogen: synthetic peptide corresponding to residues G(226)PFA SLEGFR(235) of human PTCH2.

Target Information

Mutations of the human Patched tumor suppressor gene (PTCH) have been identified in individuals with nevoid basal cell carcinoma syndrome (NBCCS) as well as in sporadic basal cell carcinomas and medulloblastomas. PTCH2 has a frameshift mutation resulting in a truncated PTCH2 protein.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.