Thermo Fisher Scientific PTCH2 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

-

Product Specifications

Species Reactivity

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Synthetic peptide corresponding to residues G(226) P F A S L E G F R(235) of human PTCH2. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:PTCH2,uniProtId:Q9Y6C5-1,ncbiNodeId:9606,antigenRange:226-235|227-235,antigenLength:1203,antigenImageFileName:PA1-4135_PTCH2_Q9Y6C5-1_Rabbit.svg,antigenImageFileNamePDP:PA1-4135_PTCH2_Q9Y6C5-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS

Contains

0.02% sodium azide

Storage conditions

Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2237892

Product Specific Information

PA1-4135 detects Patched 2 (PTCH2) in human and mouse samples.

PA1-4135 has been successfully used in Western blot procedures. By Western blot this antibody detects a ~158 kDa protein representing PTCH2 in fetal brain lysate.

The PA1-4135 immunogen is a synthetic peptide corresponding to residues G(226) P F A S L E G F R(235) of human PTCH2.

Target Information

Mutations of the human Patched tumor suppressor gene (PTCH) have been identified in individuals with the nevoid basal cell carcinoma syndrome (NBCCS) as well as in sporadic basal cell carcinomas and medulloblastomas. PTCH2 has a frameshift mutation resulting in a truncated PTCH2 protein.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.